Congenital It Is Characterised By Hyperpigmentation Already At

congenital It is characterised by hyperpigmentation already at a birth (other bodies without Changes), later joins brushes of hands. Konstitutsionalnaja hyperpigmentation is observed at chestnut-coloured children Mainly the people of the Mediterranean. brown It is characteristic for insufficiency (illness of Addisona), at To which skin hyperpigmentation is expressed in places of pressure upon it (Vertebras, interphalanx, elbow and knee joints), pleated Bodies, on surfaces, a mucous membrane of gums. To very often result , Pancreas and lungs. At these hyperpigmentation It is caused by superproduction a hormone and , in Which the sequence of amino acids is identical. - Typical sign , late skin , motley . At hyperpigmentation serovato-brown or Brown also it is indistinguishable from that at illness of Addisona, and the diagnosis Can be established by data skin at which come to light Adjournment in glands and melanin adjournment. At Late skin the diagnosis is established on , to bubbles, to stains, to changes and rashes on To skin of open parts of a body, and proves to be true presence of the increased Maintenances in urine (a parity uro-porfirina and in norm more 3:1) or red fluorescence The acidified urine.